One of the problems with prions is they tend to be very stable and stick around in the environment for a long time, even resiting heat, cold, and persisting for

One of the problems with prions is they tend to be very stable and stick around in the environment for a long time, even resiting heat, cold, and persisting for years in soil. To add on to that, when active in a human being, they can take a very long time to get to a point where symptoms emerge.