2 ms·
I don’t know if they even have enough room to encode the entire protein, that said even if they do it’s quite likely better to focus on specific amino acid chai
by dogma1138 6y ago
I don’t know if they even have enough room to encode the entire protein, that said even if they do it’s quite likely better to focus on specific amino acid chains that relate to specific structural areas of the protein that serve a critical function like interfacing with the receptors these aren’t likely to mutate without loss of function and it increases the likelihood of more targeted immune response.
If for example each vaccine selected 30 amino acid chains say 15 common ones and 15 that are varied between vaccines you can end up with vaccines that are more effective against certain mutations than others.
Realistically COVID-19 isn’t going anywhere and it will likely become very much endemic and will require a yearly vaccine especially for risk groups just like influenza.