3 ms·
Is there any reason to think it's unlikely that mRNA defects would have the same risk profile as Ibuprofen? The body is full of thresholding processes, where up
by darawk 6y ago
Is there any reason to think it's unlikely that mRNA defects would have the same risk profile as Ibuprofen? The body is full of thresholding processes, where up to X% blood concentration the organs filter things out fine, and there's no issue, but over that level danger escalates quickly. I don't know immunology basically at all, but is there some reason to think it doesn't have processes that behave like this?
- ceejayoz 6y agoYes; they're vastly different mechanisms. Ibuprofen reaches a threshold of toxicity; a level at which our body's ability to manage it gets met and then exceeded. Things go rapidly wrong at that point. Degraded mRNA just... doesn't work. It'd be a problem if all the mRNA in your cells started suddenly degrading faster than usual, for sure, but that's because you need the resulting protein output to live. If the vaccine degrades too fast, it just doesn't produce the proteins it was supposed to, but we didn't need them to function. Lost efficacy, but you don't wind up growing extra arms.