While it's possible that post-first-light dark matter can cause caustics-like effects on the background microwaves via gravitational lensing, the fluctuations i

While it's possible that post-first-light dark matter can cause caustics-like effects on the background microwaves via gravitational lensing, the fluctuations in the CMB that are anything like the |WMAP Cold Spot| are not plausibly generated that way, mostly because dark matter is simply too diffuse from the present age of the universe back to just after the formation of the CMB (which is the earliest possible time any structure can be in the foreground of the CMB). Barring something really unexpected, the Cold Spot is probably a relic of Cosmic Inflation, producing an atypical underdensity of matter-including-dark-matter. The https://en.wikipedia.org/wiki/Axis_of_evil_(cosmology) https://en.wikipedia.org/wiki/Axis_of_evil_(cosmology) is a pretty curious thing, but I think the safest bet is a combination of randomness and https://en.wikipedia.org/wiki/Pareidolia https://en.wikipedia.org/wiki/Pareidolia .