Qubes is a great distro for this, so is Kali; but support boot to USB. But even anonymizers like the TOR Router can still have their entrypoints snooped by host

Qubes is a great distro for this, so is Kali; but support boot to USB. But even anonymizers like the TOR Router can still have their entrypoints snooped by hostile nation states to target dissidents. It is extremely hard without the help of non-US ISP to be completely anonymous and un-identifiable. And let's not forget your chips may have Intel Managent Tech which is spyware you really can't shut off that monitors/injects directly into the north/south bridge (I forget which). One of the fun parts about hitting DefCon every year is how easy it is to learn about what's new in this space. I hope they don't cancel this year: the social information sharing aspect is the best part.