For classical layout, Scribus is fine. For more advanced stuff, Inkscape is really good at geometry and Krita really good at hand-drawing. If you're familiar w

For classical layout, Scribus is fine. For more advanced stuff, Inkscape is really good at geometry and Krita really good at hand-drawing. If you're familiar with web technology, headless firefox/chromium can export to PDF, following @print and @page rules. There's a bunch of new(er) CSS properties for print usecases. i don't have anything to show yet but i've been delighted trying it out