I can sympathize to your frustration. I went through a bout of similar frustration albeit for what you may consider a much more positive situation. I finally ca

I can sympathize to your frustration. I went through a bout of similar frustration albeit for what you may consider a much more positive situation. I finally came up with my idea for a startup around the same time I started a family and the recession hit. After the birth of my 2nd child in 3 years, I was extremely frustrated because I really wanted to work on my project but my family responsibilities didn't give me enough time. What I finally concluded was I didn't want to be frustrated and I had to prioritize. So I prioritized my family, stopped working on a startup and focused on my idea being a project. Since then I've put maybe 2-3 hours a week into my site, unscatter.com. It's coming along extremely slowly, but I've also been able to focus on more fun parts of the development that I wouldn't have prioritized in the past. Along way, I've come to conclusion that I really like programming, something I gave up on as doing professionally years ago when I went the sysadmin route. More importantly, I've had a ton of fun with my family. My 3 year old girl beat me 2 times in a row in Candy Land tonight and now I just finished reading Hop On Pop for probably the hundredth before putting her to bed. Looking back, I've made the right choice. We're still stuck in a townhouse that we're upside down in and is smaller than we'd like. We're still on the east coast when my wife is chomping at the bit to move back the West Coast so she can get our girls more associated with her culture (she's Native American, her tribe is Haida Gwaii which is a Canadian west coast tribe). However, we're spending the time with our girls and it shows in their behavior and attitude we're doing the right thing. Forget a startup, I'm helping build the foundation for 2 lives and while money would help it's become obvious that my time really is the better investment. So, how does this equate to your situation? Heck you posted this 7 hours ago so I don't even know if you'll ever read this. But here's my impression based on your post above. You moved back with your family to help take care of your parents who are in their 70's. You'd move, but you'd feel guilty. Look, you've already made the same choice I did, you've decided to put your family first. Obviously you love your parents, are you'd already be gone. So, love them. Cherish all the time you can have with them because you will miss them when they're gone. Forget professional momentum, you can get back on that track later. Or, try to see how you can keep that momentum going now. You can do a startup anywhere, just maybe you need to scale it down a notch. I saw below in the comments your a business guy. Awesome, start a business. Do your own coffee shop. Find something that interests you that you can build a business in within that area. If you have the skills, then you'll accomplish it. If you lack the skills but really have the drive, you'll learn the skills and accomplish it. Failures are learning experiences. First you just need to believe in yourself.