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I don't agree with this take. IVF live birth rates are something like 30% of implantations. e.g. see https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139227/ https
by theptip 6y ago
I don't agree with this take. IVF live birth rates are something like 30% of implantations. e.g. see https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139227/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139227/.
The article you're linking even says that Winston is using the wrong number, and spends most of its time explaining why he's wrong;
> Lord Winston's 1% figure was referring to the proportion of all frozen eggs thawed for use in fertility treatment which result in a pregnancy and subsequent live birth.
You have plenty of eggs; it's not particularly relevant if a single egg has a 1% chance of resulting in a live birth. The extraction process will gather something like 10 eggs (plus or minus a lot) and then later you fertilize lots of those eggs and select the best candidates for implantation. Selectively quoting the single-egg success rate provides an inaccurate picture of the actual success rates of the overall process (one that's quite obscure and therefore susceptible to people misunderstanding when articles publish misleading advice like this).
Furthermore, research shows that the primary factor determining live birth rate is the age of the eggs. As you get above 37/38 the live-birth rate starts to decrease dramatically. If you freeze your eggs at 35 then implant at age 40 then you don't see the same increase in failure rate as if you just did IVF at age 40.
IF you want to postpone having kids until your 40s, but you know you really want to have kids at that age, then freezing your eggs is a good strategy for those that can afford it.
I'm all for giving women more choices/options around child-bearing; it's already difficult enough for women to balance career and children in modern society.
> Insurance policies usually guarantee a payoff. In this case, there is no guarantee.
If you're looking to buy an insurance policy that guarantees you will get pregnant, I'm sorry to say no such thing exists. All you can do is improve your probabilities. Freezing your eggs does this.
> Women should be doing it because it’s the best option they have
Again your quote is actually arguing for freezing eggs being a good option. What would you say "sound advice" is for women that want to defer having children until their 40s, if it's not freezing their eggs?
- Goronmon 6y agoThe extraction process will gather something like 10 eggs (plus or minus a lot)... Isn't 10 minus "a lot", close to or equal to 0? Or is there something I'm missing with this phrasing?
- theptip 6y agoPerhaps I was being overly flippant as I don't have the precise distribution. I'm sure it could be zero, I don't know how often that is though. A quick Google gives 10-20 on average: https://www.arcfertility.com/how-is-ivf-done-step-by-step/#:~:text=Ovarian%20stimulation%20is%20used%20to,are%20usually%20retrieved%20for%20IVF https://www.arcfertility.com/how-is-ivf-done-step-by-step/#:....
- bdcravens 6y agoAge can affect this. We didn't freeze my wife's until her late 30s; only 4 eggs were created.
- powerslacker 6y agoI made my statement and posted those quotes because a woman should prioritize children over her career if she desires them. I don't think that there is "sound advice" for women who want to defer having children until they are in their 40s. The odds of a woman having a successful pregnancy are much better if they are under 40. It is easy to see through just the anecdotal reports that many women either thought or were convinced that freezing their eggs succeeds far more often than it actually does in the real world.