I guess my first thought is: the amount of fructose in fruit is small relative to the amount in, say, a cola. Also, fiber might mitigate the insulin response. A

I guess my first thought is: the amount of fructose in fruit is small relative to the amount in, say, a cola. Also, fiber might mitigate the insulin response. Also, we aren't eating fruits found in the wild (which is the relevant ecological context for this discussion). We have selectively bred fruits to be bigger and sweeter.