If you want less overhead, pre-compiled GPU kernel code, and a simple input/output interface for GPU computation. I wrote a similar, but arguably lighter weight

If you want less overhead, pre-compiled GPU kernel code, and a simple input/output interface for GPU computation. I wrote a similar, but arguably lighter weight solution here: https://github.com/nick-funk/radium https://github.com/nick-funk/radium It uses Cloo, so OpenCL if that's what you like. Includes examples for basic array operations as well as a full blown ray tracer so you can see how complex objects are passed to and from the GPU. Caveat: you're writing C-esque compute kernels, not C# though.