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There seems to be an inherent assumption built into all of these kinds of studies that all humans are identical interchangeable units. You don't see a lot of "t
by taneq 6y ago
There seems to be an inherent assumption built into all of these kinds of studies that all humans are identical interchangeable units. You don't see a lot of "this intervention is wildly successful in 20% of subjects and useless in the rest" type results advertised.
- heisenzombie 6y agoYeah, I get the impulse, and there are studies which try to partition subjects into “responders” and “non-responders”. The problem is if you don’t set out the partitions before you start the study then any ex post facto partitioning is fertile ground for p-hacking. The correct thing is to do the exploratory study, notice that some group seem to respond well, then run a new study “IF for the prevention of CVD in <specific subgroup>”. That’s a lot to ask, of course.
- taneq 6y agoThat makes sense. I guess the real trick is to figure out what the key distinguishing factor for that particular subgroup is...