What drugs are best at extinguishing those negative priors? Vorinostat worked for me when a slew of antidepressants did not, but it's hard to find and can have

What drugs are best at extinguishing those negative priors? Vorinostat worked for me when a slew of antidepressants did not, but it's hard to find and can have side effects. It was really astounding. I just felt normal, unafraid, but not in a weird amped up way as with Adderall. I could just talk to people fluidly and think normally.