Although this seems compelling, there is also the role of 5HT2A receptors in weighting priors as Carhart-Harris and Friston discuss in https://www.researchgate.

Although this seems compelling, there is also the role of 5HT2A receptors in weighting priors as Carhart-Harris and Friston discuss in https://www.researchgate.net/publication/333911957_REBUS_and_the_Anarchic_Brain_Toward_a_Unified_Model_of_the_Brain_Action_of_Psychedelics https://www.researchgate.net/publication/333911957_REBUS_and... While this primarily has to do with psychedelics, they address depression as well in the above.