5 ms·

So will this lead to a cure since I've tried 15 and only mirtazapine worked for a few years?

royaltjames 6y ago
God I hope so. Just found a blend that's helping me feel human for the first time in these 35 years of living. I'm in the same boat with Mirtaz, altho I'm finding success with pairing it with Viibryd. A big help is genesight testing for upfront compatibility/sensitivity for a consultancy approach, rather than spray and pray.
- pyentropy 6y ago
  There is very little evidence GeneSight results mean anything for efficacy. Tolerability and dose metabolism in the best case.
yarg 6y ago
Psilocybin genuinely works for me - when I can get it (difficult because it's class A and seasonal). The last time I had it was a bad night - I took about 7g. However, the suicidal thoughts that had been getting progressively more serious stopped overnight. I'll never touch another fucking SSRI. I'd rather not exist at all than become the unperson those things turn me into.
- winocm 6y ago
  I want to die too...
  - yarg 6y ago
    More than I want to die, I want not to be a part of the omnicidal stupidity that seems to define humanity. I really do want not to die, and I see a viable path forward with that as a result. An illegal and seasonal path. I last took a dose in July, and those malignant fucking thoughts are returning. And nurses keep telling me that psilocybin clearly has not worked (all the while advocating a pill a day, pill a day, pill a day). If you see a drowning man take a gasp of air, and the keep right on drowning that does not mean that the air did not work. The system is fucked - but try not to let it eat you.
- the_only_law 6y ago
  I was on SSRIs many years ago. I don’t recall feeling any better or worse, with them. I was also on other things with larger risks that’s thankfully didn’t materialize. But again, didn’t feel like they did anything. Unfortunately psychedelics I’ve tried just up anxiety and paranoia. My last experience had me crouched up on the couch alternating between sweating and chills, hating the time dilation and just waiting it out.
- austhrow743 6y ago
  Mushrooms are pretty easy to grow btw. If it was the difference between me feeling depressed or not I certainly wouldn't be relying on spotty supply.
  - yarg 6y ago
    I live in New Zealand - I can't afford land. The only possibility for getting around the seasonalilty is growing indoors - and I really don't have the space for that. Depression for me has caused me to spiral down - so far down that there's no apparent path back up. I've been down and out for so long that even finding work is damned near impossible - so I can never even get to the point where renting my own place is feasible.
whalesalad 6y ago
Mirtazapine was a nightmare for me. Even at high doses. I’ve tried a half dozen. My next experiment pending warmer weather here in MI: a hunt for wild psilocybin mushrooms. I’m convinced the best way to achieve my goals is to rewire my brain with psychedelic experiences.

God I hope so. Just found a blend that's helping me feel human for the first time in these 35 years of living. I'm in the same boat with Mirtaz, altho I'm finding success with pairing it with Viibryd. A big help is genesight testing for upfront compatibility/sensitivity for a consultancy approach, rather than spray and pray.

pyentropy 6y ago
There is very little evidence GeneSight results mean anything for efficacy. Tolerability and dose metabolism in the best case.

yarg 6y ago

Psilocybin genuinely works for me - when I can get it (difficult because it's class A and seasonal). The last time I had it was a bad night - I took about 7g. However, the suicidal thoughts that had been getting progressively more serious stopped overnight. I'll never touch another fucking SSRI. I'd rather not exist at all than become the unperson those things turn me into.

winocm 6y ago
I want to die too...
- yarg 6y ago
  More than I want to die, I want not to be a part of the omnicidal stupidity that seems to define humanity. I really do want not to die, and I see a viable path forward with that as a result. An illegal and seasonal path. I last took a dose in July, and those malignant fucking thoughts are returning. And nurses keep telling me that psilocybin clearly has not worked (all the while advocating a pill a day, pill a day, pill a day). If you see a drowning man take a gasp of air, and the keep right on drowning that does not mean that the air did not work. The system is fucked - but try not to let it eat you.
the_only_law 6y ago
I was on SSRIs many years ago. I don’t recall feeling any better or worse, with them. I was also on other things with larger risks that’s thankfully didn’t materialize. But again, didn’t feel like they did anything. Unfortunately psychedelics I’ve tried just up anxiety and paranoia. My last experience had me crouched up on the couch alternating between sweating and chills, hating the time dilation and just waiting it out.
austhrow743 6y ago
Mushrooms are pretty easy to grow btw. If it was the difference between me feeling depressed or not I certainly wouldn't be relying on spotty supply.
- yarg 6y ago
  I live in New Zealand - I can't afford land. The only possibility for getting around the seasonalilty is growing indoors - and I really don't have the space for that. Depression for me has caused me to spiral down - so far down that there's no apparent path back up. I've been down and out for so long that even finding work is damned near impossible - so I can never even get to the point where renting my own place is feasible.

whalesalad 6y ago

Mirtazapine was a nightmare for me. Even at high doses. I’ve tried a half dozen. My next experiment pending warmer weather here in MI: a hunt for wild psilocybin mushrooms. I’m convinced the best way to achieve my goals is to rewire my brain with psychedelic experiences.