We have new insight now into how antidepressants interface with specific signaling molecules, making them more effectively permeate the neuron cell membrane. I

We have new insight now into how antidepressants interface with specific signaling molecules, making them more effectively permeate the neuron cell membrane. It's still about chemical balance. It's a highly complex system involving more than serotonin, though. He mentions serotonin reuptake inhibitors once, but it looks like this finding applies to other substances identified as anti-depressants that aren't necessarily serotonin targeting.