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i expect we'll wind up with "this year's COVID strains" to be part of an annual flu shot cocktail. And, i expect annual flu vaccines to improve exponentially no
by hprotagonist 6y ago
i expect we'll wind up with "this year's COVID strains" to be part of an annual flu shot cocktail. And, i expect annual flu vaccines to improve exponentially now that we've neatly demonstrated the applicability of mRNA therapies for respiratory viruses!
other endemic diseases we've got largely under control are neatly enumerated by the list of childhood vaccinations, for example https://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolescent.html https://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolesc.... It's not like measles is "gone", after all.
- tachyonbeam 6y agoI agree with you but IMO there needs to be more of a political push for this to happen. We need much larger production capacity. Ideally everyone should be making mRNA vaccines, and we also need faster approval processes. We can't do a full 3-phase clinical study every time the vaccine formula is tweaked. We need faster turnaround times.
- ekianjo 6y agoThey dont do full clinical trials for yearly flu shots either...
- bryanlarsen 6y agoCOVID mutates a lot slower than the flu so it's unlikely that every year will need a COVID booster.
- throwawayboise 6y agoI'm hearing that the immunity from actually contracting and recovering from COVID only lasts about 90 days. Have any of the vaccines been shown to do any better?
- graeme 6y agoThat is....not true. There are scattered reinfections but it is far from the norm. SARS 1 and MERS generated immunity for years.
- throwawayboise 6y agoHm. My work requires COVID testing every other week. If you've actually had COVID, you get a 90 day exemption because "that's how long immunity lasts"
- hprotagonist 6y agopost-infection-and-recovery and post-vaccination are not the same.
- room500 6y agoThe CDC recommends this 90 day window because a "positive" test result is more likely to be due to your previous illness than a new infection. Therefore, testing is useless because it gives you no useful information [1] > for adults recovered from SARS-CoV-2 infection, a positive SARS-CoV-2 RT-PCR result without new symptoms during the 90 days after illness onset more likely represents persistent shedding of viral RNA than reinfection It does NOT mean that you are suddenly susceptible after 90 days - just that after 90 days, you are less likely to be actively shedding the previous infection so the tests are useful again [1] https://www.cdc.gov/coronavirus/2019-ncov/hcp/duration-isolation.html https://www.cdc.gov/coronavirus/2019-ncov/hcp/duration-isola...
- throwawayboise 6y agoThanks for clarifying that... definitely not the message that we are getting at work, which is strictly making immunity claims. This leads many people to think either "why get vaccinated if it only lasts 90 days" or worry "does this mean I will need a booster shot every 90 days"
- bluGill 6y ago
- standardUser 6y agoIf natural immunity from COVID-19 only lasted 90 days we would see millions of cases of second and third re-infections by now. Studies have found only a tiny, tiny number of confirmed reinfections within ~10 months.
- T-A 6y agohttps://www.scilifelab.se/news/a-majority-retain-protective-antibodies-against-covid-19-nine-months-after-infection https://www.scilifelab.se/news/a-majority-retain-protective-...
- yakubin 6y ago> i expect annual flu vaccines to improve exponentially This sentence doesn't mean anything.
- baxtr 6y agoWhy do you expect that? The four other endemic coronaviruses endemic in humans don’t require anyone to be vaccinated. They just cause a simple cold. Why should this one be different once it’s endemic?
- anamexis 6y agoBecause this one doesn't just cause a simple cold?
- baxtr 6y agoYes exactly. That’s because this one is still pandemic and not yet endemic.
- mikem170 6y agoIn kids it has basically that affect - no worse than the common cold. Maybe the big difference is that living adults didn't catch covid-19 as kids, because it is new. Since kids are growing up in a world with covid-19 they will catch it like any other covid-cold, priming their immune system so it never sends them to the hospital should they catch it again. Maybe this also explains why the common cold kills people sometimes. These unlucky people never caught that specific coronavirus as children, but rather when they were older and more vulnerable.