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is the infection severity angle due to testosterone's immunosuppressive effects as a steroid? are women less likely to develop severe covid-19 than men? I'm ho
by sterlind 6y ago
is the infection severity angle due to testosterone's immunosuppressive effects as a steroid? are women less likely to develop severe covid-19 than men?
I'm hoping I've gotten some extra protection by ditching testosterone for estrogen, but there's almost no data on infections in trans people on HRT.
- smt88 6y ago> is the infection severity angle due to testosterone's immunosuppressive effects as a steroid? Yes, most likely[1]. > are women less likely to develop severe covid-19 than men? Yes[2]. This was an early observation and has been observed consistently since Covid-19 was discovered. > I'm hoping I've gotten some extra protection by ditching testosterone for estrogen That's an interesting question. I'm a layperson, but I would assume the answer is yes, since testosterone levels seems to be the root cause of the sex differences in immune response. I'm sure the doctor who helped/helps you transition would know. It's possible that vitamin D (another hormone and a secosteroid) is an even more important factor than testosterone, in case you're looking for other ways to safely reduce your risk of severe Covid. 1. https://www.health.harvard.edu/blog/man-flu-really-thing-2018010413033 https://www.health.harvard.edu/blog/man-flu-really-thing-201... 2. https://www.nature.com/articles/s41467-020-19741-6 https://www.nature.com/articles/s41467-020-19741-6
- srean 6y agoHave no idea why this comment was down voted. Upvoted to compensate