2 ms·
Tetanus does not transmit person to person and so is a poor example. In particular since the coronavirus vaccines do target the pathogen. Likewise, it is not s
by graeme 6y ago
Tetanus does not transmit person to person and so is a poor example. In particular since the coronavirus vaccines do target the pathogen.
Likewise, it is not surprising that injecting a live polio virus can cause an infection. That is a different claim than saying a vaccinated person will get infected and transmit later once immune. Further, the coronavirus vaccines do not use live viruses.
Whooping cough is the example people love to bring up. I’ll paste in full my prior comment on this. The worst case example reduces transmission at least 30%! And probably more: it was completely sterilizing in 30% but may well have reduced transmissibility in other groups. And that’s the very worst case vaccine.
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I looked into this, and it does seem the vaccine reduces transmission. It just doesn’t stop it entirely. The paper below is Wikipedia’s source. Upon a close read, in the daycare there were three groups of vaccinated children:
* Those positive for antibodies but pcr negative —> had been exposed, cleared virus without infection
* those pcr positive but asymptomatic
* those pcr positive and symptomatic
About 30% were in the seropositive group which didn’t have pcr positivity. So it seems like transmission was reduced at least 30%. It’s also possible the other two groups would have had lower transmission rates than if they had had no vaccine.
If you have a more precise source I’d be interested to see it, but if this is the worst case it’s pretty good!
> We used PCR, EIA, and culture to confirm B. pertussis infection in two highly vaccinated groups of children in two day-care centers. Three (10%) of 30 2- to 3-year-old children were seropositive for recent infection; one had nasopharyngeal colonization and a clinical illness that met the modified WHO case definition. In the day-care center for the 5- to 6- year-old group, 9 (55%) of 16 children were IgM positive, 4 (25%) of whom had nasopharyngeal colonization. Of these four children, three had nonspecific cough, and only one met the modified WHO definition for pertussis. None of the children in our study, including those who met the WHO definition, had been examined by a physician before our investigation.
>Children who were seropositive and re- mained both asymptomatic and PCR negative probably had sufficient immunity from vaccines or natural boosters to protect them against persistent colonization and clinical disease. Their seropositivity could not be due to vaccine because the children were tested more than a year after having been vaccinated.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627963/pdf/10998384.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627963/pdf/109...
https://news.ycombinator.com/item?id=25903787 https://news.ycombinator.com/item?id=25903787
- oldgradstudent 6y agoI am not sure how do you draw these conclusions from the study. There's no comparison between transmission by vaccinated and non-vaccinated children, so there's no possible way of concluding that vaccination reduced transmission relative to non-vaccination.
- graeme 6y agoAmong the vaccinated students 30% showed antibodies but were pcr negative. Hence they had fought off an infection but had no trace of replication. You would not expect to see seropositive but pcr negative students if unvaccinated.