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I suspect that viral shedding reinfection with mild symptoms or total absence of symptoms is responsible for “silent super spreaders”. Recovered or vaccinated i
by sradman 6y ago
I suspect that viral shedding reinfection with mild symptoms or total absence of symptoms is responsible for “silent super spreaders”. Recovered or vaccinated individuals will need to be extra vigilant. This is really the time for near-daily rapid antigen screening tests. If this hypothesis is correct, the antibody escaping variants are like a new common cold coronavirus for the recovered/vaccinated but have equivalent outcomes to the original virus for the remaining susceptible population.
In TWiV #717 [1] guests Paul Bieniasz and Theodora Hatziioannou indicated that the variants all seem to converge on antibody escaping mutations similar to what they see in the lab. They speculated that reinfection is responsible for the selection pressure necessary to generate these variants.
[1] https://www.microbe.tv/twiv/twiv-717/ https://www.microbe.tv/twiv/twiv-717/