A founder effect population would still have some genetic variance left (Alleles A through M), but it would have less than the base population (A through Z). Th

A founder effect population would still have some genetic variance left (Alleles A through M), but it would have less than the base population (A through Z). This is a shift in allele frequencies in the population as a whole due to sampling bias. Inbreeding is reproduction by two people that are closely related (i.e. have similar alleles). Since people only have one allele in our example, that only occurs when two people with the same allele (e.g. A-A) reproduce. A-B, B-C, or any other dissimilar combination would not be inbreeding because their alleles are different, i.e. the "coefficient of inbreeding" is low. Hopefully that clarifies how they're distinct.