Space becomes an issue when trying to minimize your buffers. During a casual playthrough, it won't really matter, but if you're dealing with megabases, the dist

Space becomes an issue when trying to minimize your buffers. During a casual playthrough, it won't really matter, but if you're dealing with megabases, the distances and buffers can really impact how the smoothly a factory works, how quickly it can respond to changes. For example, not all of the "infinite research" technologies have the same science pack requirements, which changes what your base has to produce.