4 ms·

Peanuts are a great example. I am not allergic to peanuts myself, but I avoid eating them. I don't know why people become allergic to them, but there must be s

Peanuts are a great example. I am not allergic to peanuts myself, but I avoid eating them. I don't know why people become allergic to them, but there must be something in some peanuts which sets off their immune system.

jbarberu 6y ago
That's not how allergies work. People with allergies get an immune reaction to a harmless compound.
- forgotmypw17 6y ago
  I don't think you have a clue about how allergies work, with all due respect. A harmless compound can be cross-associated by the immune system just by being correlated with a harmful one. Meaning if something harmful is present in peanuts sometimes but not all the time, the immune system will associate peanut compounds with it and reject peanuts as well.
Judgmentality 6y ago
The true irony of this statement, and I want to emphasize I am not a doctor, is that you are more likely to cause a peanut allergy by avoiding it! https://directorsblog.nih.gov/2017/01/10/peanut-allergy-early-exposure-is-key-to-prevention/ https://directorsblog.nih.gov/2017/01/10/peanut-allergy-earl... Similar to germ theory, some exposure is actually good.
- im3w1l 6y ago
  From my understanding, some types of exposure promote allergy while other types of exposure prevent it.
jlund-molfese 6y ago
How far do you take that theory? People have allergies to many (normally) benign substances. Melons, natural latex, ibuprofen, pollen, etc.
- forgotmypw17 6y ago
  Generally speaking, if it wasn't in my ancestors' environment, I avoid it. Otherwise, approach with caution. Nature can be dangerous, too, but at least it's likely that someone in the past has dealt with it and lived to reproduce. With new synthetic substances, you're essentially doing alpha-testing with your irreplaceable hardware/software system...
- e_y_ 6y ago
  Pollen in particular is weird because simply being outside should expose you to some level of pollen, compared to foods like melons or peanuts that may or may not be part of your diet. I'm mildly allergic to dust mites and they're literally everywhere.
  - kelnos 6y ago
    Right. I'm currently undergoing allergy immunotherapy, so back in October I had a battery of allergy tests. Turns out I'm allergic to some trees, some grasses, pollen, mold, dust mites, and a bunch of other things. And yet my childhood from a very young age was filled with playing outside in the yard and and in the woods. Also my family had (indoor-only) cats since before I was born. My parents were allergic to them, and my sister and I are also allergic. (Wanting to get a cat is what prompted me to start the allergy shots.) So I've been exposed to cat dander since I was an infant. And yet: allergic. Some things are just hereditary, I guess. I'm sure there are some cases where not being exposed to something when young can cause you to develop allergies, but that's definitely not the only cause. Seems like there is definitely a genetic component that can moot any amount of childhood exposure.
KoftaBob 6y ago
This assumes that if your immune system reacts negatively to something, it is guaranteed to be actually harmful to the body. If our immune systems and bodies were all-knowing and perfect, then sure, that would be a valid assumption, but they're far from it.
namibj 6y ago
Yes, peanut proteins.

jbarberu 6y ago

That's not how allergies work. People with allergies get an immune reaction to a harmless compound.

forgotmypw17 6y ago
I don't think you have a clue about how allergies work, with all due respect. A harmless compound can be cross-associated by the immune system just by being correlated with a harmful one. Meaning if something harmful is present in peanuts sometimes but not all the time, the immune system will associate peanut compounds with it and reject peanuts as well.

Judgmentality 6y ago

The true irony of this statement, and I want to emphasize I am not a doctor, is that you are more likely to cause a peanut allergy by avoiding it! https://directorsblog.nih.gov/2017/01/10/peanut-allergy-early-exposure-is-key-to-prevention/ https://directorsblog.nih.gov/2017/01/10/peanut-allergy-earl... Similar to germ theory, some exposure is actually good.

im3w1l 6y ago
From my understanding, some types of exposure promote allergy while other types of exposure prevent it.

jlund-molfese 6y ago

How far do you take that theory? People have allergies to many (normally) benign substances. Melons, natural latex, ibuprofen, pollen, etc.

forgotmypw17 6y ago
Generally speaking, if it wasn't in my ancestors' environment, I avoid it. Otherwise, approach with caution. Nature can be dangerous, too, but at least it's likely that someone in the past has dealt with it and lived to reproduce. With new synthetic substances, you're essentially doing alpha-testing with your irreplaceable hardware/software system...
e_y_ 6y ago
Pollen in particular is weird because simply being outside should expose you to some level of pollen, compared to foods like melons or peanuts that may or may not be part of your diet. I'm mildly allergic to dust mites and they're literally everywhere.
- kelnos 6y ago
  Right. I'm currently undergoing allergy immunotherapy, so back in October I had a battery of allergy tests. Turns out I'm allergic to some trees, some grasses, pollen, mold, dust mites, and a bunch of other things. And yet my childhood from a very young age was filled with playing outside in the yard and and in the woods. Also my family had (indoor-only) cats since before I was born. My parents were allergic to them, and my sister and I are also allergic. (Wanting to get a cat is what prompted me to start the allergy shots.) So I've been exposed to cat dander since I was an infant. And yet: allergic. Some things are just hereditary, I guess. I'm sure there are some cases where not being exposed to something when young can cause you to develop allergies, but that's definitely not the only cause. Seems like there is definitely a genetic component that can moot any amount of childhood exposure.

KoftaBob 6y ago

This assumes that if your immune system reacts negatively to something, it is guaranteed to be actually harmful to the body. If our immune systems and bodies were all-knowing and perfect, then sure, that would be a valid assumption, but they're far from it.

namibj 6y ago

Yes, peanut proteins.