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Interesting, I hadn't known that. I imagine the short booster dose time also helps in implementation, because an individual gets maximum immunity 6 weeks after
by MereInterest 6y ago
Interesting, I hadn't known that. I imagine the short booster dose time also helps in implementation, because an individual gets maximum immunity 6 weeks after the first dose (4 weeks pause + 2 weeks) rather than 28 weeks (6 month pause + 2 weeks) for a longer pause. Having a longer pause to maximize individual immunity might not be the fastest way to maximize population immunity during an ongoing pandemic.
- nicoburns 6y agoI'm not sure about that. Here in the UK we've gone with a 12 week gap precisely because it allows us to vaccinate more of the population more quickly.
- mlyle 6y agoFirst dose gets you to 80% efficacy after about 10 days. If you e.g. produce 1 dose per month, you're way better off giving the doses to ABCDEFABCDEF than AABBCCDDEEFF. Six people are 80% protected after 6 months, instead of 3 people 95% protected after 6 months... assuming that everyone ends up at the same efficacy at the end (which we don't know). But... we know this is probably effective-- probably even more effective after the delayed second dose.. which isn't the same as showing that it's effective in a study.
- MereInterest 6y agoGood point, I hadn't been aware that the first dose was that effective without the booster.