3 ms·
The results in Figure 3 are certainly promising. Has anyone been able to find the mentioned supplementary material though? > A post-hoc exploratory analysis of
by boulos 6y ago
The results in Figure 3 are certainly promising. Has anyone been able to find the mentioned supplementary material though?
> A post-hoc exploratory analysis of immunogenicity in subgroups of participants aged ≥55-<65, ≥65-74 and ≥75 years was performed (Tables S6 and S7). Increases in levels of anti-SARS-CoV-2-spike bAb and nAb at days 29 and post-second vaccination at both the 50 and 100 ug doses were generally comparable across the age subgroups and with those observed in the younger (18-55 years) study participants. Seroconversion rates were also comparable across the age groups and with those in the younger participants. It should be noted that the small size of the ≥75 year-old subgroup (n=22) precludes definitive conclusions to be made.
There doesn't seem to be any link to supplementary material at either the Elsevier page [1] nor the NIH page [2]. The clinical trial registration [3] suggests that there was an update just a few days ago, so perhaps they're just waiting to upload a new PDF?
[1] https://www.sciencedirect.com/science/article/pii/S0264410X21001535 https://www.sciencedirect.com/science/article/pii/S0264410X2...
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871769/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871769/
[3] https://clinicaltrials.gov/ct2/show/study/NCT04405076 https://clinicaltrials.gov/ct2/show/study/NCT04405076
- jessriedel 6y agoProbably not available as part of the journal's "pre-proof" process. You'll likely have to wait until the formal publication date. > These versions will undergo additional copyediting, typesetting and review, and may not yet have full ScienceDirect functionality. For example, supplementary files may still need to be added, links to references may not resolve yet, etc. The text could still change before final publication. https://service.elsevier.com/app/answers/detail/a_id/22799/supporthub/sciencedirect/ https://service.elsevier.com/app/answers/detail/a_id/22799/s...