Throughout the pandemic we have seen many small studies that have had small hints of efficacy which later shows up as a null result in larger studies. Mostly th

Throughout the pandemic we have seen many small studies that have had small hints of efficacy which later shows up as a null result in larger studies. Mostly this can be attributed to various sources of statical noise. In this case though, a 90% reduction is unlikely to be a null result, even though it is likely to be an overestimate. The signal is much higher than the background.