They absolutely have been legally commercialized. In the United States (and presumably elsewhere) you can easily find a doctor who will legally prescribe you a

They absolutely have been legally commercialized. In the United States (and presumably elsewhere) you can easily find a doctor who will legally prescribe you a host of steroids, growth hormones, and various other "anti-aging medications". My understanding is that many of them don't do bloodwork to test existing hormone levels and many that do use very liberal interpretations of what standard levels in men should be at a given age, etc. Think of the "pill mills" that lead to the opiod crisis where as long as you had the cash someone would write a prescription. Note that I'm not insinuating similar levels of risk or harm, merely pointing out the flexibility of medical ethics for some doctors in these areas. Use your favorite search engine and search "anti-aging clinic". They're in many US cities, available online, and a popular medical tourism destination. EDIT: I also suspect these kinds of medical "interventions" are prevalent in Hollywood and elsewhere. For example, Hugh Jackman in Wolverine. This guy was born in 1968, which puts him at ~44 years old during filming. Look at his physique as a 44 year old man and tell me that was just from broccoli and chicken (especially considering his physique in roles leading up to Wolverine). I'm not saying it's impossible, I'm just saying that the chances that so many of these mid to late 40s Hollywood actors have a physique that would be excellent on a 20-25 year old isn't likely due to just freak genetics, diet, and hard work at the gym. Especially when the budgets of these films can easily exceed $100 million.