While interesting, even if anti-bodies are detected in the end we have an N=1. The average random person doesn't get this. A single result is not generalizabl

While interesting, even if anti-bodies are detected in the end we have an N=1. The average random person doesn't get this. A single result is not generalizable. It kind of reminds me of the @justsaysinmice twitter account [1] which replies to relevant studies with "IN MICE". So many factors can confound this type of work. Some big ones: 1) Does this work in general population? 2) How long does the antibody response last? 3) Does this work on variants? 4) Are there cases when this should not be used? I remember a reference to one of the early SARS vaccines. It was promising, until they found it caused immune responses resulting in lung damage on people who had SARS (can’t find the exact paper but [2] highlights some of the concerns then and now). [1] https://twitter.com/justsaysinmice https://twitter.com/justsaysinmice [2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318931/#!po=2.00000 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318931/#!po=2....