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I'm not suprised to see this post so popular on Less Wrong/the rational community. I can easily imagine the fascination they have for crazy scientists doing exp

by flr03 6y ago

I'm not suprised to see this post so popular on Less Wrong/the rational community. I can easily imagine the fascination they have for crazy scientists doing experimentations on them selves, cutting all the corners and operating at fair distance of ethical concerns. I'm not very convinced by the "Motivations" section of the article by the way, but that's a nice stunt nonetheless, and quite fascinating indeed.

angry_octet 6y ago
They've romanticised the stories of scientists self-testing and mixed it with the stories of Jenner and Fleming, misinterpreting their unethical (Jenner) and credit grabbing (Fleming) ways as brilliant contrarianism.
shuckles 6y ago
This is unnecessarily dismissive. IIRC, Josiah Zayner home brewed a vaccine which led to a positive antibody test, which is in and of itself a pretty impressive outcome given the resources he had available to deploy.
- throwaway2245 6y ago
  The Bloomberg link posted above states he had a positive antibody test before administering the home brew.
  - shuckles 6y ago
    That link seems to be quite incomplete. For example, it never mentions that there were two other people involved, at least one of whom didn’t have the same confounding issues. Here are the results: https://docs.google.com/document/d/1WTuRBuy74KlaBzLrd0aTZl852nhPNCWL06aB7wY1JKk/edit https://docs.google.com/document/d/1WTuRBuy74KlaBzLrd0aTZl85...
- xirbeosbwo1234 6y ago
  There's no such thing as being too dismissive of LessWrong. It is among the more useless parts of the Internet. I fell for it hook, line, and sinker when I was younger and don't want to see anyone make the same mistakes I did. Stay in school, kids. Or at least don't get your wisdom from a guy whose magnum opus is the world's worst Harry Potter fanfiction.
  - shuckles 6y ago
    To the extent you are posting this as a warning to rationally inclined young people to not be seduced by the discourse on LessWrong, your warning is likely to be perceived as cranky by that audience and therefore ineffective. You may want to revisit your style, if that’s indeed your goal.
- stonogo 6y ago
  With the end result that he has no idea whether it actually did anything, and has declared all of medicine to be 'too messy.'

by flr03 6y ago

angry_octet 6y ago

They've romanticised the stories of scientists self-testing and mixed it with the stories of Jenner and Fleming, misinterpreting their unethical (Jenner) and credit grabbing (Fleming) ways as brilliant contrarianism.

shuckles 6y ago

This is unnecessarily dismissive. IIRC, Josiah Zayner home brewed a vaccine which led to a positive antibody test, which is in and of itself a pretty impressive outcome given the resources he had available to deploy.

throwaway2245 6y ago
The Bloomberg link posted above states he had a positive antibody test before administering the home brew.
- shuckles 6y ago
  That link seems to be quite incomplete. For example, it never mentions that there were two other people involved, at least one of whom didn’t have the same confounding issues. Here are the results: https://docs.google.com/document/d/1WTuRBuy74KlaBzLrd0aTZl852nhPNCWL06aB7wY1JKk/edit https://docs.google.com/document/d/1WTuRBuy74KlaBzLrd0aTZl85...
xirbeosbwo1234 6y ago
There's no such thing as being too dismissive of LessWrong. It is among the more useless parts of the Internet. I fell for it hook, line, and sinker when I was younger and don't want to see anyone make the same mistakes I did. Stay in school, kids. Or at least don't get your wisdom from a guy whose magnum opus is the world's worst Harry Potter fanfiction.
- shuckles 6y ago
  To the extent you are posting this as a warning to rationally inclined young people to not be seduced by the discourse on LessWrong, your warning is likely to be perceived as cranky by that audience and therefore ineffective. You may want to revisit your style, if that’s indeed your goal.
stonogo 6y ago
With the end result that he has no idea whether it actually did anything, and has declared all of medicine to be 'too messy.'