5 ms·

>We studied mice, but the effect we observed is equivalent to kids having a Western diet, high in fat and sugar Is there any evidence beyond correlation that h

>We studied mice, but the effect we observed is equivalent to kids having a Western diet, high in fat and sugar Is there any evidence beyond correlation that high fat diets are unhealthy? Also the researchers measured mice intestinal biome at 14 weeks, given that the lifespan of bacteria is probably similar whether in mice or in humans, I wonder if the comparison to human lifespan is valid, considering that a transition that takes x mice-years may only take y human-months, so to speak.

zemvpferreira 6y ago
we have good evidence that partially hydrogenated oils are directly responsible for cardiovascular disease, I believe. "High healthy fats" diets? Probably not as much of a well-studied link there. I would 100% agree that a high-sugar low-fat diet is more dangerous than eating high-fat low-sugar, but high-fat high-sugar is a hell of a lot worse than either of the other combinations - and a more common diet in the population at large. That's probably more relevant to this study, as limited as it is.
shaicoleman 6y ago
Not all fats are created equal. There's data pointing that Omega-6 fatty acids (primarily vegetable/seed oils and trans fats) are harmful. See the following talk by Dr. Chris Knobbe: https://youtu.be/7kGnfXXIKZM https://youtu.be/7kGnfXXIKZM You can jump here for the studies: https://youtu.be/7kGnfXXIKZM?t=2020 https://youtu.be/7kGnfXXIKZM?t=2020
Gibbon1 6y ago
I think the trouble is define 'high fat diet' What kind of fats are we talking about exactly. Trans-fats? Rancid fats. Fats in cured meat? Fats from seed oils? What kind of seeds? Vegetable fats? If so again what kind? Maybe you think olive oil is okay. What if I told you 90% of olive oil is adulterated? Animal fat? What's that animal been eating? The last one is interesting. Before WWII frozen chicken really wasn't a thing because frozen chicken tasted rancid after it was thawed. Someone figured out you could fix that by switching the feed from linseed to corn.

zemvpferreira 6y ago

we have good evidence that partially hydrogenated oils are directly responsible for cardiovascular disease, I believe. "High healthy fats" diets? Probably not as much of a well-studied link there. I would 100% agree that a high-sugar low-fat diet is more dangerous than eating high-fat low-sugar, but high-fat high-sugar is a hell of a lot worse than either of the other combinations - and a more common diet in the population at large. That's probably more relevant to this study, as limited as it is.

shaicoleman 6y ago

Not all fats are created equal. There's data pointing that Omega-6 fatty acids (primarily vegetable/seed oils and trans fats) are harmful. See the following talk by Dr. Chris Knobbe: https://youtu.be/7kGnfXXIKZM https://youtu.be/7kGnfXXIKZM You can jump here for the studies: https://youtu.be/7kGnfXXIKZM?t=2020 https://youtu.be/7kGnfXXIKZM?t=2020

Gibbon1 6y ago

I think the trouble is define 'high fat diet' What kind of fats are we talking about exactly. Trans-fats? Rancid fats. Fats in cured meat? Fats from seed oils? What kind of seeds? Vegetable fats? If so again what kind? Maybe you think olive oil is okay. What if I told you 90% of olive oil is adulterated? Animal fat? What's that animal been eating? The last one is interesting. Before WWII frozen chicken really wasn't a thing because frozen chicken tasted rancid after it was thawed. Someone figured out you could fix that by switching the feed from linseed to corn.