NASA pegs the risk of loss of crew for the Dragon at 1 in 276 (https://www.businessinsider.com/nasa-spacex-crew-dragon-loss-crew-mission-failure-chances-probabi

NASA pegs the risk of loss of crew for the Dragon at 1 in 276 (https://www.businessinsider.com/nasa-spacex-crew-dragon-loss-crew-mission-failure-chances-probability-2020-5); https://www.businessinsider.com/nasa-spacex-crew-dragon-loss... the demonstrated risk on the Shuttle over the lifetime of the program ended up being 1 in 68 (2 in 135 launches). For comparison, the risk on a commercial airline flight is less than one in a million.