It's a difficult one though - say I have left menu, and a sidebar on the right, and a central column with my copy. Very roughly, at about ~1350px (so neatly dis

It's a difficult one though - say I have left menu, and a sidebar on the right, and a central column with my copy. Very roughly, at about ~1350px (so neatly displayed on a generic 1440 laptop) I have about 250*2 (500px) for my sidebars, about 800px for my central column, which at a decent font size will give me a 'right-ish' about of words per line, and a few more pixels for gutters. As you start to make that smaller - 1200, 1100, something has to change. We can maybe adjust the font size in the main column, maybe there's some flexibility to shrink the sidebars (but maybe there isn't, because we need an ad in there, and that can't be resized). So we have to adjust - lose a sidebar to a hamburger menu, or change our horizontal menu at the top to include the most clicked links (and not the ten links we have before). Maybe the search bar becomes an icon, because it's more important we push the "Buy Now" button than give people an option to search, etc etc. It's an art - what do people need the most? What will make them convert? What can we remove first? What resolutions are most used, and how do we optimise for that?