You can assume that USB mice are going to become increasingly unlikely to work with those as time goes on - they're just passive adapters that instruct the mous

You can assume that USB mice are going to become increasingly unlikely to work with those as time goes on - they're just passive adapters that instruct the mouse "hey, someone is trying to plug you in with an adapter to a PS/2 port" and hoping that the mouse knows how to switch protocols. As PS/2 becomes a deep legacy standard, the likelihood is that mouse manufacturers will simply stop bothering to include that capability.