> One of my favorite signs you might have ADHD. Caffeine doesn't do anything for you and/or makes you sleepy. Caffeine is an adenosine A2A antagonist, which ha

> One of my favorite signs you might have ADHD. Caffeine doesn't do anything for you and/or makes you sleepy. Caffeine is an adenosine A2A antagonist, which has therapeutic potential in ADHD, except the half-like makes it an improbable candidate. Ironically, I just started taking an adenosine a2a antagonist, known as Nourianz (istradefylline) (link: https://www.nourianz.com/ https://www.nourianz.com/), as a last-resort drug for my severe restless legs syndrome, which has been going phenomenally well. I also have ADHD combined type (inattention and hyperactivity), and fairly severely. I take Vyvanse for my ADHD. Anyways, I have been taking the the istradefylline for a week now, and it has made a tremendous difference in many of my ADHD symptoms. Additionally, it greatly increased my sense of wellbeing within 1-2 hours of initially taking it, and it has been sustained for the entire week. Thanks to istradefylline I can now focus seamlessly and without effort. I can just "lock in" to whatever I want to do. Before, it would require some static force ("friction") to be able to "lock in" my concentration to do the task. I can also now just focus, without hyperfocusing. It now comes naturally to me. I also no longer find myself pacing around the house aimlessly. I also do not randomly get up from my seat or fidget hardcore. I can also lock back into a flow state without effort if I am disrupted. I hope you find this interesting! The adenosine a2a antagonist made a huge difference in both my restless legs syndrome and ADHD symptoms. I cannot imagine NOT being on this medication for my ADHD.