It depends what you're optimizing for. Alpine is subtly different for python builds: * It uses musl-c. It's not glibc, it's different. Not necessarily better

It depends what you're optimizing for. Alpine is subtly different for python builds: * It uses musl-c. It's not glibc, it's different. Not necessarily better or worse. * You can't use manylinux1 wheels with alpine, so if you've got python/c extensions, you're going to be building them instead of installing upstream binaries. So cue the need for a dev toolchain, and a much longer install time. And once you have all that, you're running a different version in dev/prod, which is one of those things that docker is supposed to be good at fixing.