Sounds like you may not be familiar with Django, but it's honestly an amazing option if you want something that's mature, stable, well documented and full stack

Sounds like you may not be familiar with Django, but it's honestly an amazing option if you want something that's mature, stable, well documented and full stack (the latter being key - one of the only ORMs I don't hate). The biggest problem for Django and Python in general to me is more in the line of the scalability (performance) question. You are simply forced to put one or even two layers in front of it with a multi-process architecture just to get it to a baseline deployable state (in this case, traefik + gunicorn). But the good news is there are so many people doing that it really isn't a problem. And it turns out you probably want that architecture anyway (probably best if your application server isn't also doing your TLS etc).