Keepass can take advantage of the secure desktop to unlock the password database, and has multiple methods for entering passwords, including a method that mixes

Keepass can take advantage of the secure desktop to unlock the password database, and has multiple methods for entering passwords, including a method that mixes clipboard actions and auto-typing. It's not perfect, and anything that can log keys and monitor the clipboard would be able to sniff passwords. That said, it's a pretty good set of mitigations.