As long as you flash a sane layout to the controller it's not very hard unless it's a very small keyboard. 40% keyboards like the Planck are a bit harder becaus

As long as you flash a sane layout to the controller it's not very hard unless it's a very small keyboard. 40% keyboards like the Planck are a bit harder because you lose the number row, but anything bigger isn't a big issue. Switching back to a normal staggered layout doesn't take long for me, but I wouldn't like doing it every day.