Computationally relevant information is sometimes embedded in runtime state (for example, yeast prions), but this is very rare. For small bacteria, you can swit

Computationally relevant information is sometimes embedded in runtime state (for example, yeast prions), but this is very rare. For small bacteria, you can switch out the entire genome with a new genome and have them continue living just fine. For all intents and purposes on an engineering level, everything is/can be encoded in DNA.