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The paper discusses this a bit: Identification of an individual organophosphorus compound is a complex and time-consuming process. [9] In fact, ascertaining th
by Natsu 6y ago
The paper discusses this a bit:
Identification of an individual organophosphorus compound is a complex and time-consuming process. [9] In fact, ascertaining the involvement of a novichok agent and its biotransformation products in this case was only achieved several days after establishing the diagnosis of cholinesterase inhibitor poisoning and did not affecttherapeutic decisions.Organophosphorus nerve agents exert the same mechanism of action as do organophosphorus pesti-cides (ie, inhibition of acetylcholinesterase) and clinical management is largely based on experience with organo-phosphorus pesticide poisonings, which still pose a major health burden in southeast Asia, with more than 100000 deaths per year. [10] Clinical diagnosis of organophosphorus poisoning should be straightforward.
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[9] John H, van der Schans MJ, Koller M, et al. Fatal sarin poisoning in Syria 2013: forensic verification within an international laboratory network. Forensic Toxicol 2018; 36: 61–71.
[10] Mew EJ, Padmanathan P, Konradsen F, et al. The global burden of fatal self-poisoning with pesticides 2006–15: systematic review. J Affect Disord 2017; 219: 93–104.