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The primary benefit of the vaccine over 'natural' immunity (other than avoiding actual exposure) is the emphasis on neutralizing antibody formation.
by wittyreference 6y ago
The primary benefit of the vaccine over 'natural' immunity (other than avoiding actual exposure) is the emphasis on neutralizing antibody formation.
- AndrewBissell 6y agoI had assumed the vaccine was also intended/believed to induce T-cell response, is that not the case? Given that they disappear within a matter of months after a natural infection, how long are the antibodies from the vaccines believed to last?
- wittyreference 6y agoOh, it is. I meant that that is also part of 'natural' immunization. The distinction between the 'natural' exposure and the vaccine is that the natural exposure targets a number of epitopes, which may or may not include effective neutralizing antibodies against the spike protein; the vaccine, on the other hand, only offers the spike as an antigen, so you know you're generating neutralizing ab.
- jupp0r 6y agoThere are vaccines in development that also target the N-protein.