I wrote this article a while back that compares setting up a Python development environment for web development with and without Docker: https://nickjanetakis.c

I wrote this article a while back that compares setting up a Python development environment for web development with and without Docker: https://nickjanetakis.com/blog/setting-up-a-python-development-environment-with-and-without-docker https://nickjanetakis.com/blog/setting-up-a-python-developme... The TL;DR is there's a lot of things to set up yourself without Docker in order to run a typical web application and it's different depending on what OS / version you use. Some of these things are unrelated to Python too, such as running PostgreSQL, Redis, etc. but these are very important to your overall application. Docker unifies that entire set up and the barrier of entry is installing Docker once and then learning a bit about it.