The Great Filter thesis is that there has to be one or more very low probability events in the Drake Equation. However, as per my other comments, you can updat

The Great Filter thesis is that there has to be one or more very low probability events in the Drake Equation. However, as per my other comments, you can update the distributions of your parameters in different ways, such that none of the events in the Drake equation have a particularly low probability. Then the Great Filter disappears and there's no specific or few set of events to point to - it's just that the probability of all events succeeding in combination is extremely low.