I use a mix of syncthing and seafile. Syncthing is very simple to setup and pretty much set-and-forget. Seafile is more involved but the end result is closer to

I use a mix of syncthing and seafile. Syncthing is very simple to setup and pretty much set-and-forget. Seafile is more involved but the end result is closer to the classic Dropbox experience. If you’re not interested in self-hosting and just want a straight Dropbox replacement, I’d look into Nextcloud providers.