3 ms·

This is half a story. What treatments were tried and did the patient survive? The letter is here but I can't access it from my phone: https://www.sciencedirect

This is half a story. What treatments were tried and did the patient survive? The letter is here but I can't access it from my phone: https://www.sciencedirect.com/science/article/pii/S266729602030015X https://www.sciencedirect.com/science/article/pii/S266729602... Bummer.

YeGoblynQueenne 6y ago
He survived but was still beging treated when the report was published (11 January 2020): Initial exam was remarkable for O2 saturation on room air of 92%, heart rate of 100, and blood pressure of 75/47. He was noted to be ill-appearing with dry mucous membranes, mild cyanosis of the lips and nail beds, and jaundiced skin. His abdomen was diffusely tender to palpation without rebound or guarding. He was grossly confused and unable to meaningfully participate in an interview. Laboratory studies revealed thrombocytopenia, hyponatremia, hyperkalemia, hypochloremia, hypocalcemia, acute renal insufficiency, and acute liver injury. Cardiac workup revealed elevated cardiac enzymes and his electrocardiogram was remarkable for sinus tachycardia and early repolarization. Mr. X was then transferred to the ICU for evidence of multi-organ failure and he was started on intravenous fluids, multiple vasopressors, broad spectrum antibiotics, and anti-fungal medications. His hospital course was further complicated by septic shock and acute respiratory failure requiring intubation on hospital day two and disseminated intravascular coagulation requiring plasmapheresis. Cultures confirmed bacteremia (ultimately cultured as Brevibacillus) and fungemia (ultimately cultured as Psilocybe cubensis – i.e. the species of mushroom he had injected was now growing in his blood). He was treated for a total of 22 days in the hospital with eight of them in the ICU. At the time of writing, he is currently still being treated with a long-term regimen of daptomycin, meropenem, and voriconazole. https://www.sciencedirect.com/science/article/pii/S266729602030015X https://www.sciencedirect.com/science/article/pii/S266729602...

YeGoblynQueenne 6y ago

He survived but was still beging treated when the report was published (11 January 2020): Initial exam was remarkable for O2 saturation on room air of 92%, heart rate of 100, and blood pressure of 75/47. He was noted to be ill-appearing with dry mucous membranes, mild cyanosis of the lips and nail beds, and jaundiced skin. His abdomen was diffusely tender to palpation without rebound or guarding. He was grossly confused and unable to meaningfully participate in an interview. Laboratory studies revealed thrombocytopenia, hyponatremia, hyperkalemia, hypochloremia, hypocalcemia, acute renal insufficiency, and acute liver injury. Cardiac workup revealed elevated cardiac enzymes and his electrocardiogram was remarkable for sinus tachycardia and early repolarization. Mr. X was then transferred to the ICU for evidence of multi-organ failure and he was started on intravenous fluids, multiple vasopressors, broad spectrum antibiotics, and anti-fungal medications. His hospital course was further complicated by septic shock and acute respiratory failure requiring intubation on hospital day two and disseminated intravascular coagulation requiring plasmapheresis. Cultures confirmed bacteremia (ultimately cultured as Brevibacillus) and fungemia (ultimately cultured as Psilocybe cubensis – i.e. the species of mushroom he had injected was now growing in his blood). He was treated for a total of 22 days in the hospital with eight of them in the ICU. At the time of writing, he is currently still being treated with a long-term regimen of daptomycin, meropenem, and voriconazole. https://www.sciencedirect.com/science/article/pii/S266729602030015X https://www.sciencedirect.com/science/article/pii/S266729602...