If by 'generic PCIe slot' you mean an NVMe slot that I have to buy janky adapters for, and figure out mechanical mounting for, then yeah. But I'm not sure I'd l

If by 'generic PCIe slot' you mean an NVMe slot that I have to buy janky adapters for, and figure out mechanical mounting for, then yeah. But I'm not sure I'd like to depend on that. And then I might as well do that with an Intel NUC, or just go for a normal mini-ITX motherboard.