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Does the 501.v2 strain resist vaccine antibodies as well, or only things like the antibody cocktail / convalescent plasma therapy?
by pageandrew 6y ago
Does the 501.v2 strain resist vaccine antibodies as well, or only things like the antibody cocktail / convalescent plasma therapy?
- whoisburbansky 6y agoThe first paper describes the effect of mRNA based vaccine derived serum on both variants, showing that both variants are affected about equally by the vaccine, if I’m not horribly mistaken?
- alevskaya 6y agoThe first study is only studying the effect of the N501Y mutation as found in several emergent strains, not the E484K mutation.
- whoisburbansky 6y agoYes, sorry, I phrased that badly. I meant N501 and Y501 when I said both variants here.
- alevskaya 6y agoWhat I meant by sera above was general adaptive immunity. It's likely to partially resist past immunity from both vaccines (esp. from the spike-only vaccines: moderna, pfizer, etc) and natural infections from older strains. We'll probably know a lot more about it soon, but we may need to update our vaccines to include this mutant class.