The use case I'm surprised we don't see is for refurbishing embedded devices without changing software. Plenty of things like tills and gambling machines were

The use case I'm surprised we don't see is for refurbishing embedded devices without changing software. Plenty of things like tills and gambling machines were built around things like Pentium IIIs running embedded flavours of WinXP. The software isn't necessarily an issue (if it's not exposed to the outside world) but eventually the hardware is going to die. One of these boards would be an undisputable upgrade-- fast enough for purpose, but also fanless, no spinning-rust disc, and lower electrical consuption. It would require some careful design decisions to provide, say, a video and I/O solutions with WinXP drivers. Imagine one with ISA and PCI slots!