I don't have a link handy, but I recall watching a documentary where a bunch of college students participated in a study that involved waking them every time th

I don't have a link handy, but I recall watching a documentary where a bunch of college students participated in a study that involved waking them every time they reached REM state. After 6 days they started becoming psychotic. After 7 days someone stepped in and aborted the project as the students were going fully psychotic. I don't recall who intervened. They may not have died but if I recall correctly, they would have killed each other.