This kind of gets into why I don't think it's worth the tradeoffs. You can get a desk big enough to support a tripod and monitor without sacrificing ergonomics,

This kind of gets into why I don't think it's worth the tradeoffs. You can get a desk big enough to support a tripod and monitor without sacrificing ergonomics, but then you have to have a massive desk. My current desk is 32" deep, and I'm certain that bringing the monitor close enough to make room for a tripod on the desk would involve bringing the monitor too close for comfort. In my specific case it would also necessitate giving up the gas-arm that my monitor is attached to since it only clips to the back of the desk, and I don't want to give that up. You can make it work, if you rearrange your entire office space around this requirement. I personally wouldn't recommend it, but to each their own.