3 ms·
Anyone knows if the small number of people who do get side-effects from a vaccine would have been been likely to get a severe form of the disease if infected?
by abdullahkhalids 6y ago
Anyone knows if the small number of people who do get side-effects from a vaccine would have been been likely to get a severe form of the disease if infected?
Or if the side-effect subset is random.
- epistasis 6y agoFor the side effects of: * Injection site pain * Fatigue * Headache * Muscle pain * Chills * Joint pain * Fever The effects are too mild and short term to pose an interesting research question, I would think. For the more sever side effect of swollen lymph nodes, it has not been investigated, though that might provide enough immune system insight to be an interesting question to pursue. The only other adverse event, Bell's Palsy, is currently indistinguishable from the background rate of occurrence, so I would doubt that anybody is investigating that. There's a big methodological problem too: you can either get an extreme reaction to COVID-19, or you can have side effects from the vaccine, but a person going through one would poison the results of the other. So to come up with some sort of experiment, you'd need some sort or prognostic based on biomarkers that was strong and convincing enough to think it was related to what you're predicting, which we definitely don't have yet. Then you'd need to cross tab between effects. Potentially possible, but it relies on a pretty big discovery that would have better uses!